Antibody-Conjugated Nanoparticles for Biomedical Applications
Joint Authors
González-Fernández, África
Arruebo, Manuel
Valladares, Mónica
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-24, 24 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-03
Country of Publication
Egypt
No. of Pages
24
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
Nanoscience and Nanotechnology have found their way into the fields of Biotechnology and Medicine.
Nanoparticles by themselves offer specific physicochemical properties that they do not exhibit in bulk form, where materials show constant physical properties regardless of size.
Antibodies are nanosize biological products that are part of the specific immune system.
In addition to their own properties as pathogens or toxin neutralizers, as well as in the recruitment of immune elements (complement, improving phagocytosis, cytotoxicity antibody dependent by natural killer cells, etc.), they could carry several elements (toxins, drugs, fluorochroms, or even nanoparticles, etc.) and be used in several diagnostic procedures, or even in therapy to destroy a specific target.
The conjugation of antibodies to nanoparticles can generate a product that combines the properties of both.
For example, they can combine the small size of nanoparticles and their special thermal, imaging, drug carrier, or magnetic characteristics with the abilities of antibodies, such as specific and selective recognition.
The hybrid product will show versatility and specificity.
In this review, we analyse both antibodies and nanoparticles, focusing especially on the recent developments for antibody-conjugated nanoparticles, offering the researcher an overview of the different applications and possibilities of these hybrid carriers.
American Psychological Association (APA)
Arruebo, Manuel& Valladares, Mónica& González-Fernández, África. 2009. Antibody-Conjugated Nanoparticles for Biomedical Applications. Journal of Nanomaterials،Vol. 2009, no. 2009, pp.1-24.
https://search.emarefa.net/detail/BIM-472445
Modern Language Association (MLA)
Arruebo, Manuel…[et al.]. Antibody-Conjugated Nanoparticles for Biomedical Applications. Journal of Nanomaterials No. 2009 (2009), pp.1-24.
https://search.emarefa.net/detail/BIM-472445
American Medical Association (AMA)
Arruebo, Manuel& Valladares, Mónica& González-Fernández, África. Antibody-Conjugated Nanoparticles for Biomedical Applications. Journal of Nanomaterials. 2009. Vol. 2009, no. 2009, pp.1-24.
https://search.emarefa.net/detail/BIM-472445
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472445