![](/images/graphics-bg.png)
Relation of High-Density Lipoprotein Cholesterol and Apoprotein A1 Levels with Presence and Severity of Coronary Obstruction
Joint Authors
Sáez de Lafuente, J. P.
Santos, M.
Iriarte, J. A.
Molinero, E.
Sagastagoitia, J. D.
Sáez, Y.
Vacas, M.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The aim of this work was to investigate the relationship between different lipids parameters with presence and severity of coronary obstruction angiographically evaluated.
897 patients (629 men and 268 women) underwent an angiography and blood extraction to determine concentrations of lipid markers: total cholesterol (TC), HDL cholesterol (HDLc), triglycerides, LDL cholesterol (LDLc), apolipoprotein A1 (apoA1), apolipoprotein B100 (apoB), non-HDL cholesterol and total cholesterol/HDLc, apoB100/apoA1 and LDLc/HDLc ratios.
Multivariate analysis revealed that low HDLc levels were independently associated with the presence of coronary obstruction (OR: 0.982, 95% CI 0.969–0.996).
In relation to severity of coronary stenosis, only apoA1 levels (OR: 0.990, 95% CI 0.980–1.000) and apoB/apoA1 ratio (OR: 3.243, 95% CI 1.095–9.608) were independent predictors.
Our study demonstrated that HDLc was the only lipid parameter negatively and significantly associated with the presence of coronary obstruction, whereas apoA1 levels and apoB/apoA1 ratio were independent predictors of stenosis severity.
American Psychological Association (APA)
Sáez, Y.& Vacas, M.& Santos, M.& Sáez de Lafuente, J. P.& Sagastagoitia, J. D.& Molinero, E.…[et al.]. 2012. Relation of High-Density Lipoprotein Cholesterol and Apoprotein A1 Levels with Presence and Severity of Coronary Obstruction. ISRN Vascular Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-472651
Modern Language Association (MLA)
Sáez, Y.…[et al.]. Relation of High-Density Lipoprotein Cholesterol and Apoprotein A1 Levels with Presence and Severity of Coronary Obstruction. ISRN Vascular Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-472651
American Medical Association (AMA)
Sáez, Y.& Vacas, M.& Santos, M.& Sáez de Lafuente, J. P.& Sagastagoitia, J. D.& Molinero, E.…[et al.]. Relation of High-Density Lipoprotein Cholesterol and Apoprotein A1 Levels with Presence and Severity of Coronary Obstruction. ISRN Vascular Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-472651
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472651