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Bone Marrow Stem Cells Added to a Hydroxyapatite Scaffold Result in Better Outcomes after Surgical Treatment of Intertrochanteric Hip Fractures
Joint Authors
Lopes, M. Ascenção
Cabral, A. T.
Santos, J. Domingos
Gutierres, Manuel
Pinto, R.
Torres, Joao
van Eck, Carola
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
Intertrochanteric hip fractures occur in the proximal femur.
They are very common in the elderly and are responsible for high rates of morbidity and mortality.
The authors hypothesized that adding an autologous bone marrow stem cells concentrate (ABMC) to a hydroxyapatite scaffold and placing it in the fracture site would improve the outcome after surgical fixation of intertrochanteric hip fractures.
Material and Methods.
30 patients were randomly selected and divided into 2 groups of 15 patients, to receive either the scaffold enriched with the ABMC (Group A) during the surgical procedure, or fracture fixation alone (Group B).
Results.
There was a statistically significant difference in favor of group A at days 30, 60, and 90 for Harris Hip Scores (HHS), at days 30 and 60 for VAS pain scales, for bedridden period and time taken to start partial and total weight bearing (P<0.05).
Discussion.
These results show a significant benefit of adding a bone marrow enriched scaffold to surgical fixation in intertrochanteric hip fractures, which can significantly reduce the associated morbidity and mortality rates.
Conclusion.
Bone marrow stem cells added to a hydroxyapatite scaffold result in better outcomes after surgical treatment of intertrochanteric hip fractures.
American Psychological Association (APA)
Torres, Joao& Gutierres, Manuel& Lopes, M. Ascenção& Santos, J. Domingos& Cabral, A. T.& Pinto, R.…[et al.]. 2014. Bone Marrow Stem Cells Added to a Hydroxyapatite Scaffold Result in Better Outcomes after Surgical Treatment of Intertrochanteric Hip Fractures. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-472653
Modern Language Association (MLA)
Torres, Joao…[et al.]. Bone Marrow Stem Cells Added to a Hydroxyapatite Scaffold Result in Better Outcomes after Surgical Treatment of Intertrochanteric Hip Fractures. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-472653
American Medical Association (AMA)
Torres, Joao& Gutierres, Manuel& Lopes, M. Ascenção& Santos, J. Domingos& Cabral, A. T.& Pinto, R.…[et al.]. Bone Marrow Stem Cells Added to a Hydroxyapatite Scaffold Result in Better Outcomes after Surgical Treatment of Intertrochanteric Hip Fractures. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-472653
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472653