![](/images/graphics-bg.png)
Bilateral Atypical Femoral Fractures in a Patient with Multiple Myeloma Treated with Intravenous Bisphosphonate Therapy
Joint Authors
Sairyo, Koichi
Goto, Tomohiro
Yoshioka, Shinji
Hamada, Daisuke
Egawa, Hiroshi
Iwame, Toshiyuki
Tonogai, Ichiro
Goda, Yuichiro
Tsutsui, Takahiko
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-22
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Bisphosphonates are currently the standard approach to managing bone disease in multiple myeloma.
Bisphosphonates have high bone affinity that inhibits osteoclastic activity and additionally reduces the growth factors released from malignant or osteoblastic cells, thereby impairing abnormal bone remodeling which leads to osteolysis.
However, patients of multiple myeloma may be at a higher risk of atypical femoral fractures because the treatment for malignant myeloma requires notably higher cumulative doses of bisphosphonates.
Here we present a patient with bilateral atypical femoral fractures and multiple myeloma treated with intravenous bisphosphonate therapy.
American Psychological Association (APA)
Tonogai, Ichiro& Goto, Tomohiro& Hamada, Daisuke& Iwame, Toshiyuki& Yoshioka, Shinji& Tsutsui, Takahiko…[et al.]. 2014. Bilateral Atypical Femoral Fractures in a Patient with Multiple Myeloma Treated with Intravenous Bisphosphonate Therapy. Case Reports in Orthopedics،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-472705
Modern Language Association (MLA)
Tonogai, Ichiro…[et al.]. Bilateral Atypical Femoral Fractures in a Patient with Multiple Myeloma Treated with Intravenous Bisphosphonate Therapy. Case Reports in Orthopedics No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-472705
American Medical Association (AMA)
Tonogai, Ichiro& Goto, Tomohiro& Hamada, Daisuke& Iwame, Toshiyuki& Yoshioka, Shinji& Tsutsui, Takahiko…[et al.]. Bilateral Atypical Femoral Fractures in a Patient with Multiple Myeloma Treated with Intravenous Bisphosphonate Therapy. Case Reports in Orthopedics. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-472705
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472705