Thermal Study of a Newly Synthesized Cu(II) Complex Binding to Bovine β-Lactoglobulin
Joint Authors
Behbehani, Gholamreza Rezaei
Barzegar, Lyla
Divsalar, Adeleh
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We have investigated the interactions between β-lactoglobulin, BLG, and new synthesized Cu(II) complex (2,2′-dibipyridine Cu(II) chloride) using isothermal titration calorimetry (ITC) methods at different temperatures of 298 and 310 K.
The heats of BLG + Cu(II) interactions are reported and analyzed in terms of the extended solvation theory for calculation of binding and thermodynamic parameters of the interaction.
The results suggested that binding of Cu(II) complex on BLG resulted in significant changes on the tertiary structure and conformation of protein via increasing of hydrophobicity and inducing partially unfolded structure in BLG which has a good agreement with the solvation parameters recovered by the extended solvation model suggesting destabilization of the protein.
American Psychological Association (APA)
Divsalar, Adeleh& Barzegar, Lyla& Behbehani, Gholamreza Rezaei. 2012. Thermal Study of a Newly Synthesized Cu(II) Complex Binding to Bovine β-Lactoglobulin. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-472768
Modern Language Association (MLA)
Divsalar, Adeleh…[et al.]. Thermal Study of a Newly Synthesized Cu(II) Complex Binding to Bovine β-Lactoglobulin. Journal of Chemistry No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-472768
American Medical Association (AMA)
Divsalar, Adeleh& Barzegar, Lyla& Behbehani, Gholamreza Rezaei. Thermal Study of a Newly Synthesized Cu(II) Complex Binding to Bovine β-Lactoglobulin. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-472768
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472768