Proteins Reprogramming : Present and Future
Joint Authors
Dong, Jianwen
Yang, Yang
Liu, Bin
Rong, Limin
Pang, Mao
Zhang, Liangming
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Induced pluripotent stem cells (iPSCs) are of great clinical interest for they are derived from one’s own somatic cells and have the potential of committed differentiation without immunological rejection after autografting.
However, the use of viral and other modified vectors may still cause tumorigenesis due to chromosome insertion mutation, leading to limited practical use.
iPSCs generated by reprogramming proteins overcome the potential safety risk and complicated manipulation procedures, thus they own better application prospective, yet some technical difficulties need to be studied and resolved, for instance, low reprogramming efficiency, unclear transduction, and reprogramming mechanism.
In this paper, we summarize the current progress of proteins reprogramming technology for generation of iPSCs and discuss the promising efficiency-improved reprogramming methods by proteins plus other kinds of chemical compounds.
American Psychological Association (APA)
Yang, Yang& Liu, Bin& Dong, Jianwen& Zhang, Liangming& Pang, Mao& Rong, Limin. 2012. Proteins Reprogramming : Present and Future. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-472779
Modern Language Association (MLA)
Yang, Yang…[et al.]. Proteins Reprogramming : Present and Future. The Scientific World Journal No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-472779
American Medical Association (AMA)
Yang, Yang& Liu, Bin& Dong, Jianwen& Zhang, Liangming& Pang, Mao& Rong, Limin. Proteins Reprogramming : Present and Future. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-472779
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472779