The Effect of Antihypertensive Drugs on Endothelial Function as Assessed by Flow-Mediated Vasodilation in Hypertensive Patients
Joint Authors
Kotani, Kazuhiko
Miyamoto, Michiaki
Taniguchi, Nobuyuki
Ishibashi, Shun
Source
International Journal of Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-29
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Endothelial dysfunction is found in hypertensive patients and may serve as a prognostic marker of future cardiovascular events.
Endothelial function can be assessed noninvasively by flow-mediated vasodilation (FMD).
The goal of this paper is to summarize comprehensively the clinical trials that investigated the effects of antihypertensive drugs on endothelial function assessed by FMD in hypertensive patients.
A PubMed-based search found 38 clinical trial papers published from January 1999 to June 2011.
Significant improvement of FMD after antihypertensive treatment was shown in 43 of 71 interventions (among 38 clinical trial papers).
Angiotensin II receptor blockers and angiotensin converting enzyme inhibitors appeared to improve FMD more than other drug types.
Antihypertensive treatment can improve endothelial dysfunction when assessed by FMD, although there are conflicting data that require further research.
American Psychological Association (APA)
Miyamoto, Michiaki& Kotani, Kazuhiko& Ishibashi, Shun& Taniguchi, Nobuyuki. 2012. The Effect of Antihypertensive Drugs on Endothelial Function as Assessed by Flow-Mediated Vasodilation in Hypertensive Patients. International Journal of Vascular Medicine،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-472784
Modern Language Association (MLA)
Miyamoto, Michiaki…[et al.]. The Effect of Antihypertensive Drugs on Endothelial Function as Assessed by Flow-Mediated Vasodilation in Hypertensive Patients. International Journal of Vascular Medicine No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-472784
American Medical Association (AMA)
Miyamoto, Michiaki& Kotani, Kazuhiko& Ishibashi, Shun& Taniguchi, Nobuyuki. The Effect of Antihypertensive Drugs on Endothelial Function as Assessed by Flow-Mediated Vasodilation in Hypertensive Patients. International Journal of Vascular Medicine. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-472784
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472784