Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis

Joint Authors

Matsuhisa, Munehide
Matsuoka, Taka-aki
Kaneto, Hideaki
Katakami, Naoto

Source

Mediators of Inflammation

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-02-16

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Diseases

Abstract EN

Type 2 diabetes is the most prevalent and serious metabolic disease all over the world, and its hallmarks are pancreatic β-cell dysfunction and insulin resistance.

Under diabetic conditions, chronic hyperglycemia and subsequent augmentation of reactive oxygen species (ROS) deteriorate β-cell function and increase insulin resistance which leads to the aggravation of type 2 diabetes.

In addition, chronic hyperglycemia and ROS are also involved in the development of atherosclerosis which is often observed under diabetic conditions.

Taken together, it is likely that ROS play an important role in the development of type 2 diabetes and atherosclerosis.

American Psychological Association (APA)

Kaneto, Hideaki& Katakami, Naoto& Matsuhisa, Munehide& Matsuoka, Taka-aki. 2010. Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-472833

Modern Language Association (MLA)

Kaneto, Hideaki…[et al.]. Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis. Mediators of Inflammation No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-472833

American Medical Association (AMA)

Kaneto, Hideaki& Katakami, Naoto& Matsuhisa, Munehide& Matsuoka, Taka-aki. Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-472833

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-472833