Stereotactic Body Radiotherapy for Metastatic Lung Cancer as Oligo-Recurrence : An Analysis of 42 Cases
Joint Authors
Niibe, Yuzuru
Takahashi, Wataru
Yamashita, Hideomi
Hayakawa, Kazushige
Shiraishi, Kenshiro
Nakagawa, Keiichi
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To investigate the outcome and toxicity of stereotactic body radiotherapy (SBRT) in patients with oligo-recurrence cancer in the lung (ORCL).
Methods and Materials.
A retrospective review of 42 patients with ORCL who underwent SBRT in our two hospitals was conducted.
We evaluated the outcome and adverse effects after SBRT for ORCL.
Results.
All patients finished their SBRT course without interruptions of toxicity reasons.
The median follow-up period was 20 months (range, 1–90 months).
The 2-year local control rate and overall survival were 87% (95% CI, 75–99%) and 65% (95% CI, 48–82%).
As for prognostic factor, the OS of patients with a short disease-free interval (DFI) <31.9 months, between the initial therapy and SBRT for ORCL, was significantly worse than the OS of long DFI ≧31.9 months (P<0.05).
The most commonly observed late effect was radiation pneumonitis.
One patient had grade 4 gastrointestinal toxicity (perforation of gastric tube).
No other ≧ grade 3 acute and late adverse events occurred.
There were no treatment-related deaths during this study.
Conclusions.
In patients with ORCL, radical treatment with SBRT is safe and provides a chance for long-term survival by offering favorable local control.
American Psychological Association (APA)
Takahashi, Wataru& Yamashita, Hideomi& Niibe, Yuzuru& Shiraishi, Kenshiro& Hayakawa, Kazushige& Nakagawa, Keiichi. 2012. Stereotactic Body Radiotherapy for Metastatic Lung Cancer as Oligo-Recurrence : An Analysis of 42 Cases. Pulmonary Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-472849
Modern Language Association (MLA)
Takahashi, Wataru…[et al.]. Stereotactic Body Radiotherapy for Metastatic Lung Cancer as Oligo-Recurrence : An Analysis of 42 Cases. Pulmonary Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-472849
American Medical Association (AMA)
Takahashi, Wataru& Yamashita, Hideomi& Niibe, Yuzuru& Shiraishi, Kenshiro& Hayakawa, Kazushige& Nakagawa, Keiichi. Stereotactic Body Radiotherapy for Metastatic Lung Cancer as Oligo-Recurrence : An Analysis of 42 Cases. Pulmonary Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-472849
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472849