Salvage Therapy of Multiple Myeloma : The New Generation Drugs
Joint Authors
Di Raimondo, Cosimo
Vetro, Calogero
Cavalli, Maide
Schinocca, Elena
Chiarenza, Annalisa
La Fauci, Alessia
Di Martina, Valentina
Conticello, Concetta
Di Raimondo, Francesco
Romano, Alessandra
Parrinello, Nunziatina Laura
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-19
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
During the past decade, overall results of treatment of multiple myeloma (MM) have been improved and survival curves are now significantly better with respect to those obtained with historical treatment.
These improvements are linked to a deeper knowledge of the biology of disease and to the introduction in clinical practice of drugs with different mechanism of action such as proteasome inhibitors and immunomodulatory drugs (IMiDs).
However, MM remains in most cases an incurable disease.
For patients who relapse after treatment with novel agents, the prognosis is dismal and new drugs and therapeutic strategies are required for continued disease control.
In this review, we summarize new insights in salvage therapy for relapsed/refractory MM as emerging from recent clinical trials exploring the activity of bendamustine, new generation proteasome inhibitors, novel IMiDs, monoclonal antibodies, and drugs interfering with growth pathways.
American Psychological Association (APA)
Romano, Alessandra& Conticello, Concetta& Cavalli, Maide& Vetro, Calogero& Di Raimondo, Cosimo& Di Martina, Valentina…[et al.]. 2014. Salvage Therapy of Multiple Myeloma : The New Generation Drugs. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-472910
Modern Language Association (MLA)
Romano, Alessandra…[et al.]. Salvage Therapy of Multiple Myeloma : The New Generation Drugs. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-472910
American Medical Association (AMA)
Romano, Alessandra& Conticello, Concetta& Cavalli, Maide& Vetro, Calogero& Di Raimondo, Cosimo& Di Martina, Valentina…[et al.]. Salvage Therapy of Multiple Myeloma : The New Generation Drugs. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-472910
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-472910