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Complete Genome Sequence of Rothia mucilaginosa DY-18 : A Clinical Isolate with Dense Meshwork-Like Structures from a Persistent Apical Periodontitis Lesion
Joint Authors
Mashimo, Chiho
Fukushima, Hisanori
Sugimori, Chieko
Yamanaka, Takeshi
Yamane, Kazuyoshi
Nambu, Takayuki
Leung, Kai-Poon
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Rothia mucilaginosa is an opportunistic pathogen in the human oral cavity and pharynx.
We found that R.
mucilaginosa DY-18, a clinical isolate from a persistent apical periodontitis lesion, had biofilm-like structures.
Similar structures were also observed on R.
mucilaginosa ATCC25296.
To further study these structures, we determined the complete genome sequence of DY-18 and found it a 2.26-Mb chromosome.
Regarding stress responsive systems known to affect biofilm formation in many bacteria, DY-18 genome possessed only two sigma factor genes.
One of these encoded an additional sigma factor whose promoter-binding activity may be regulated in response to environmental stimuli.
Additionally, several genes assigned to two-component signal transduction systems were presented in this genome.
To the best of our knowledge, this is the first complete genome of R.
mucilaginosa species and our data raise the possibility that this organism regulates the biofilm phenotype through these stress responsive systems.
American Psychological Association (APA)
Yamane, Kazuyoshi& Nambu, Takayuki& Yamanaka, Takeshi& Mashimo, Chiho& Sugimori, Chieko& Leung, Kai-Poon…[et al.]. 2010. Complete Genome Sequence of Rothia mucilaginosa DY-18 : A Clinical Isolate with Dense Meshwork-Like Structures from a Persistent Apical Periodontitis Lesion. Sequencing،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-473028
Modern Language Association (MLA)
Yamane, Kazuyoshi…[et al.]. Complete Genome Sequence of Rothia mucilaginosa DY-18 : A Clinical Isolate with Dense Meshwork-Like Structures from a Persistent Apical Periodontitis Lesion. Sequencing No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-473028
American Medical Association (AMA)
Yamane, Kazuyoshi& Nambu, Takayuki& Yamanaka, Takeshi& Mashimo, Chiho& Sugimori, Chieko& Leung, Kai-Poon…[et al.]. Complete Genome Sequence of Rothia mucilaginosa DY-18 : A Clinical Isolate with Dense Meshwork-Like Structures from a Persistent Apical Periodontitis Lesion. Sequencing. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-473028
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473028