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Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration
Joint Authors
Patra, R. C.
Swarup, D.
Rautray, Amiya K.
Source
Veterinary Medicine International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Oxidative stress has been implicated to play a role, at least in part, in pathogenesis of many disease conditions and toxicities in animals.
Overproduction of reactive oxygen species and free radicals beyond the cells intrinsic capacity to neutralize following xenobiotics exposure leads to a state of oxidative stress and resultant damages of lipids, protein, and DNA.
Lead and cadmium are the common environmental heavy metal pollutants and have widespread distribution.
Both natural and anthropogenic sources including mining, smelting, and other industrial processes are responsible for human and animal exposure.
These pollutants, many a times, are copollutants leading to concurrent exposure to living beings and resultant synergistic deleterious health effects.
Several mechanisms have been explained for the damaging effects on the body system.
Of late, oxidative stress has been implicated in the pathogenesis of the lead- and cadmium-induced pathotoxicity.
Several ameliorative measures to counteract the oxidative damage to the body system aftermath or during exposure to these toxicants have been assessed with the use of antioxidants.
The present review focuses on mechanism of lead- and cadmium-induced oxidate damages and the ameliorative measures to counteract the oxidative damage and pathotoxicity with the use of supplemented antioxidants for their beneficial effects.
American Psychological Association (APA)
Patra, R. C.& Rautray, Amiya K.& Swarup, D.. 2011. Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration. Veterinary Medicine International،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-473035
Modern Language Association (MLA)
Patra, R. C.…[et al.]. Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration. Veterinary Medicine International No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-473035
American Medical Association (AMA)
Patra, R. C.& Rautray, Amiya K.& Swarup, D.. Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration. Veterinary Medicine International. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-473035
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473035