Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration

Joint Authors

Patra, R. C.
Swarup, D.
Rautray, Amiya K.

Source

Veterinary Medicine International

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-03-20

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Zoology

Abstract EN

Oxidative stress has been implicated to play a role, at least in part, in pathogenesis of many disease conditions and toxicities in animals.

Overproduction of reactive oxygen species and free radicals beyond the cells intrinsic capacity to neutralize following xenobiotics exposure leads to a state of oxidative stress and resultant damages of lipids, protein, and DNA.

Lead and cadmium are the common environmental heavy metal pollutants and have widespread distribution.

Both natural and anthropogenic sources including mining, smelting, and other industrial processes are responsible for human and animal exposure.

These pollutants, many a times, are copollutants leading to concurrent exposure to living beings and resultant synergistic deleterious health effects.

Several mechanisms have been explained for the damaging effects on the body system.

Of late, oxidative stress has been implicated in the pathogenesis of the lead- and cadmium-induced pathotoxicity.

Several ameliorative measures to counteract the oxidative damage to the body system aftermath or during exposure to these toxicants have been assessed with the use of antioxidants.

The present review focuses on mechanism of lead- and cadmium-induced oxidate damages and the ameliorative measures to counteract the oxidative damage and pathotoxicity with the use of supplemented antioxidants for their beneficial effects.

American Psychological Association (APA)

Patra, R. C.& Rautray, Amiya K.& Swarup, D.. 2011. Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration. Veterinary Medicine International،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-473035

Modern Language Association (MLA)

Patra, R. C.…[et al.]. Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration. Veterinary Medicine International No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-473035

American Medical Association (AMA)

Patra, R. C.& Rautray, Amiya K.& Swarup, D.. Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration. Veterinary Medicine International. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-473035

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-473035