Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers
Joint Authors
Memon, Najma
Solangi, Amber R.
Shaikh, Huma I.
Source
Chromatography Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Implementation of Brij-35, a nonionic surfactant, as a mobile phase for separation of positional isomers is investigated.
Chromolith C-18 SpeedROD is used as a stationary phase.
The effect of surfactant and organic modifier (propanol) concentration on the separation of some selected isomers is studied and evaluated in terms of linear solvation energy relationship (LSER).
Shape selectivity is assessed by α value of sorbic and benzoic acid, which is found to be 1.339 by using mobile phase composed of 0.5% aqueous solutions of Brij-35 and propanol in 9 : 1.
Isomers of parabens, nitroanilines, nitrophenols, and quinolinols are successfully separated using mobile phases composed of various percentages of surfactant and propanol.
System constants for nonionic MLC using LSER analysis show that hydrogen bond basicity and dipolarity may be major contributors to selectivity, while excess molar refraction helps fine-tuning the separation which also imparts unique selectivity to nonionic surfactants as compared to ionic ones.
American Psychological Association (APA)
Memon, Najma& Shaikh, Huma I.& Solangi, Amber R.. 2012. Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers. Chromatography Research International،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-473104
Modern Language Association (MLA)
Memon, Najma…[et al.]. Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers. Chromatography Research International No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-473104
American Medical Association (AMA)
Memon, Najma& Shaikh, Huma I.& Solangi, Amber R.. Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers. Chromatography Research International. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-473104
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473104