Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers

Joint Authors

Memon, Najma
Solangi, Amber R.
Shaikh, Huma I.

Source

Chromatography Research International

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-02-12

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Chemistry

Abstract EN

Implementation of Brij-35, a nonionic surfactant, as a mobile phase for separation of positional isomers is investigated.

Chromolith C-18 SpeedROD is used as a stationary phase.

The effect of surfactant and organic modifier (propanol) concentration on the separation of some selected isomers is studied and evaluated in terms of linear solvation energy relationship (LSER).

Shape selectivity is assessed by α value of sorbic and benzoic acid, which is found to be 1.339 by using mobile phase composed of 0.5% aqueous solutions of Brij-35 and propanol in 9 : 1.

Isomers of parabens, nitroanilines, nitrophenols, and quinolinols are successfully separated using mobile phases composed of various percentages of surfactant and propanol.

System constants for nonionic MLC using LSER analysis show that hydrogen bond basicity and dipolarity may be major contributors to selectivity, while excess molar refraction helps fine-tuning the separation which also imparts unique selectivity to nonionic surfactants as compared to ionic ones.

American Psychological Association (APA)

Memon, Najma& Shaikh, Huma I.& Solangi, Amber R.. 2012. Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers. Chromatography Research International،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-473104

Modern Language Association (MLA)

Memon, Najma…[et al.]. Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers. Chromatography Research International No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-473104

American Medical Association (AMA)

Memon, Najma& Shaikh, Huma I.& Solangi, Amber R.. Selectivity of Brij-35 in Micellar Liquid Chromatographic Separation of Positional Isomers. Chromatography Research International. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-473104

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-473104