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High Grade Glioma Mimicking Voltage Gated Potassium Channel Complex Associated Antibody Limbic Encephalitis
Joint Authors
Delamont, R. S.
Pablo-Fernandez, E. De
Athauda, Dilan
Source
Case Reports in Neurological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Though raised titres of voltage gated potassium channel (VGKC) complex antibodies have been occasionally associated with extracranial tumours, mainly presenting as Morvan's Syndrome or neuromyotonia, they have not yet been reported to be associated with an intracranial malignancy.
This is especially important as misdiagnosis of these conditions and delay of the appropriate treatment can have important prognostic implications.
We describe a patient with a high grade glioma presenting with clinical, radiological, and serological features consistent with the diagnosis of VGKC antibody associated limbic encephalitis (LE).
This is the first association between a primary brain tumour and high titre of VGKC complex antibodies.
Clinicoradiological progression despite effective immunosuppressive treatment should prompt clinicians to look for alternative diagnoses.
Further studies to elucidate a possible association between VGKC complex and other surface antigen antibodies with primary brain tumours should be carried out.
American Psychological Association (APA)
Athauda, Dilan& Delamont, R. S.& Pablo-Fernandez, E. De. 2014. High Grade Glioma Mimicking Voltage Gated Potassium Channel Complex Associated Antibody Limbic Encephalitis. Case Reports in Neurological Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-473160
Modern Language Association (MLA)
Athauda, Dilan…[et al.]. High Grade Glioma Mimicking Voltage Gated Potassium Channel Complex Associated Antibody Limbic Encephalitis. Case Reports in Neurological Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-473160
American Medical Association (AMA)
Athauda, Dilan& Delamont, R. S.& Pablo-Fernandez, E. De. High Grade Glioma Mimicking Voltage Gated Potassium Channel Complex Associated Antibody Limbic Encephalitis. Case Reports in Neurological Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-473160
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473160