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Moxifloxacin (Avelox) Induced Thrombotic Thrombocytopenic Purpura
Joint Authors
Surana, Sikander P.
Multz, Alan S.
Sardinas, Zahily
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-11
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We report a case of a 66-year-old African-American female who presented with complaints of progressively worsening weakness, shortness of breath on minimal exertion, lethargy for the last few days, and short episodes of aphasia lasting 20–30 seconds.
Prior to presentation, she was treated with two courses of moxifloxacin for sinusitis.
Laboratory examination was remarkable for anemia and thrombocytopenia with elevated lactate dehydrogenase and no evidence of renal failure.
Peripheral smear showed numerous schistocytes and she was diagnosed with thrombotic thrombocytopenic purpura.
Moxifloxacin was identified as the offending agent.
The patient was treated with prednisone and plasmapheresis.
To the best of our knowledge, this is the first reported case of thrombotic thrombocytopenic purpura associated with the use of moxifloxacin.
Although rare, physicians should be aware of this serious complication associated with its use.
American Psychological Association (APA)
Surana, Sikander P.& Sardinas, Zahily& Multz, Alan S.. 2012. Moxifloxacin (Avelox) Induced Thrombotic Thrombocytopenic Purpura. Case Reports in Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-473186
Modern Language Association (MLA)
Surana, Sikander P.…[et al.]. Moxifloxacin (Avelox) Induced Thrombotic Thrombocytopenic Purpura. Case Reports in Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-473186
American Medical Association (AMA)
Surana, Sikander P.& Sardinas, Zahily& Multz, Alan S.. Moxifloxacin (Avelox) Induced Thrombotic Thrombocytopenic Purpura. Case Reports in Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-473186
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473186