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A Rare Case of Immune Reconstitution Inflammatory Syndrome Development in an Immunocompromised Patient with Progressive Multifocal Leukoencephalopathy and Multicentric Castleman’s Disease
Joint Authors
Jayam-Trouth, Annapurni
Kurukumbi, Mohankumar
Solieman, Noha
Dunlap, Shariff
Chapman, Sherita
Steiner, Sheldon
Source
Case Reports in Neurological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Immune reconstitution inflammatory syndrome (IRIS) development in HIV with preexistent progressive multifocal leukoencephalopathy (PML) has been extensively studied.
PML-IRIS typically manifests clinically as new or worsening neurologic symptoms in conjunction with enlarging CNS lesions and occurs in approximately 10–20 percent of HIV-infected patients with PML who begin HAART.
Likewise, Multicentric Castleman’s Disease (MCD), a rare malignant lymphoproliferative disorder, has a strong and well-known association with HIV.
Our case provides a rare instance of PML-IRIS in combination with MCD in an HIV-positive individual.
The combination of all three diseases has never been reported in the literature.
Both MCD and PML were present during initial determination of HIV infection in our patient and their disease courses were altered during the subsequent development of IRIS.
American Psychological Association (APA)
Kurukumbi, Mohankumar& Steiner, Sheldon& Dunlap, Shariff& Chapman, Sherita& Solieman, Noha& Jayam-Trouth, Annapurni. 2013. A Rare Case of Immune Reconstitution Inflammatory Syndrome Development in an Immunocompromised Patient with Progressive Multifocal Leukoencephalopathy and Multicentric Castleman’s Disease. Case Reports in Neurological Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-473321
Modern Language Association (MLA)
Kurukumbi, Mohankumar…[et al.]. A Rare Case of Immune Reconstitution Inflammatory Syndrome Development in an Immunocompromised Patient with Progressive Multifocal Leukoencephalopathy and Multicentric Castleman’s Disease. Case Reports in Neurological Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-473321
American Medical Association (AMA)
Kurukumbi, Mohankumar& Steiner, Sheldon& Dunlap, Shariff& Chapman, Sherita& Solieman, Noha& Jayam-Trouth, Annapurni. A Rare Case of Immune Reconstitution Inflammatory Syndrome Development in an Immunocompromised Patient with Progressive Multifocal Leukoencephalopathy and Multicentric Castleman’s Disease. Case Reports in Neurological Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-473321
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473321