![](/images/graphics-bg.png)
Neuromyelitis Optica : An Antibody-Mediated Disorder of the Central Nervous System
Joint Authors
Source
Neurology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-29
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Neuromyelitis optica (NMO) is a recurrent inflammatory disease that preferentially targets the optic nerves and spinal cord leading to blindness and paralysis.
The hallmarks of NMO include bilateral optic neuritis and longitudinally extensive transverse myelitis.
Woman and African Americans are overrepresented in the US patient population.
NMO is associated with the NMO-IgG biomarker, which targets the aquaporin-4 water channel on astrocytes.
The humoral pathology of NMO lesions include IgG and IgM deposits and infiltration by granulocytes suggesting that the NMO-IgG may be involved in the pathogenesis of disease.
This review of the recent NMO literature covers the clinical features, epidemiology, radiology and pathology of disease and includes discussion of the important basic science research work in the field.
American Psychological Association (APA)
Oh, Jiwon& Levy, Michael. 2012. Neuromyelitis Optica : An Antibody-Mediated Disorder of the Central Nervous System. Neurology Research International،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-473337
Modern Language Association (MLA)
Oh, Jiwon& Levy, Michael. Neuromyelitis Optica : An Antibody-Mediated Disorder of the Central Nervous System. Neurology Research International No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-473337
American Medical Association (AMA)
Oh, Jiwon& Levy, Michael. Neuromyelitis Optica : An Antibody-Mediated Disorder of the Central Nervous System. Neurology Research International. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-473337
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473337