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Regularization in Retrieval-Driven Classification of Clustered Microcalcifications for Breast Cancer
Joint Authors
Nishikawa, Robert M.
Jing, Hao
Yang, Yongyi
Source
International Journal of Biomedical Imaging
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We propose a regularization based approach for case-adaptive classification in computer-aided diagnosis (CAD) of breast cancer.
The goal is to improve the classification accuracy on a query case by making use of a set of similar cases retrieved from an existing library of known cases.
In the proposed approach, a prior is first derived from a traditional CAD classifier (which is typically pre-trained offline on a set of training cases).
It is then used together with the retrieved similar cases to obtain an adaptive classifier on the query case.
We consider two different forms for the regularization prior: one is fixed for all query cases and the other is allowed to vary with different query cases.
In the experiments the proposed approach is demonstrated on a dataset of 1,006 clinical cases.
The results show that it could achieve significant improvement in numerical efficiency compared with a previously proposed case adaptive approach (by about an order of magnitude) while maintaining similar (or better) improvement in classification accuracy; it could also adapt faster in performance with a small number of retrieved cases.
Measured by the area of under the ROC curve (AUC), the regularization based approach achieved AUC = 0.8215, compared with AUC = 0.7329 for the baseline classifier (P-value = 0.001).
American Psychological Association (APA)
Jing, Hao& Yang, Yongyi& Nishikawa, Robert M.. 2012. Regularization in Retrieval-Driven Classification of Clustered Microcalcifications for Breast Cancer. International Journal of Biomedical Imaging،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-473556
Modern Language Association (MLA)
Jing, Hao…[et al.]. Regularization in Retrieval-Driven Classification of Clustered Microcalcifications for Breast Cancer. International Journal of Biomedical Imaging No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-473556
American Medical Association (AMA)
Jing, Hao& Yang, Yongyi& Nishikawa, Robert M.. Regularization in Retrieval-Driven Classification of Clustered Microcalcifications for Breast Cancer. International Journal of Biomedical Imaging. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-473556
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473556