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Reparative Dentinogenesis Induced by Mineral Trioxide Aggregate : A Review from the Biological and Physicochemical Points of View
Joint Authors
Yoshiba, Kunihiko
Okiji, Takashi
Source
International Journal of Dentistry
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-28
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
This paper aims to review the biological and physicochemical properties of mineral trioxide aggregate (MTA) with respect to its ability to induce reparative dentinogenesis, which involves complex cellular and molecular events leading to hard-tissue repair by newly differentiated odontoblast-like cells.
Compared with that of calcium hydroxide-based materials, MTA is more efficient at inducing reparative dentinogenesis in vivo.
The available literature suggests that the action of MTA is attributable to the natural wound healing process of exposed pulps, although MTA can stimulate hard-tissue-forming cells to induce matrix formation and mineralization in vitro.
Physicochemical analyses have revealed that MTA not only acts as a “calcium hydroxide-releasing” material, but also interacts with phosphate-containing fluids to form apatite precipitates.
MTA also shows better sealing ability and structural stability, but less potent antimicrobial activity compared with that of calcium hydroxide.
The clinical outcome of direct pulp capping and pulpotomy with MTA appears quite favorable, although the number of controled prospective studies is still limited.
Attempts are being conducted to improve the properties of MTA by the addition of setting accelerators and the development of new calcium silicate-based materials.
American Psychological Association (APA)
Okiji, Takashi& Yoshiba, Kunihiko. 2009. Reparative Dentinogenesis Induced by Mineral Trioxide Aggregate : A Review from the Biological and Physicochemical Points of View. International Journal of Dentistry،Vol. 2009, no. 2009, pp.1-12.
https://search.emarefa.net/detail/BIM-473637
Modern Language Association (MLA)
Okiji, Takashi& Yoshiba, Kunihiko. Reparative Dentinogenesis Induced by Mineral Trioxide Aggregate : A Review from the Biological and Physicochemical Points of View. International Journal of Dentistry No. 2009 (2009), pp.1-12.
https://search.emarefa.net/detail/BIM-473637
American Medical Association (AMA)
Okiji, Takashi& Yoshiba, Kunihiko. Reparative Dentinogenesis Induced by Mineral Trioxide Aggregate : A Review from the Biological and Physicochemical Points of View. International Journal of Dentistry. 2009. Vol. 2009, no. 2009, pp.1-12.
https://search.emarefa.net/detail/BIM-473637
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473637