The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis
Joint Authors
Antunes, Ricardo F.
Dumitriu, Ingrid E.
Kaski, Juan Carlos
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-22
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses.
T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial roles in the development and progression of atherosclerosis.
Costimulatory receptors are a class of molecules expressed by T lymphocytes that regulate the activation of T cells and the generation of effector T-cell responses.
In this review we present the roles of costimulatory receptors of the tumour necrosis factor receptor (TNFR) superfamily in atherosclerosis and discuss the implications for future therapies that could be used to specifically modulate the immune response of pathogenic T cells in this disease.
American Psychological Association (APA)
Antunes, Ricardo F.& Kaski, Juan Carlos& Dumitriu, Ingrid E.. 2011. The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-473654
Modern Language Association (MLA)
Antunes, Ricardo F.…[et al.]. The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-16.
https://search.emarefa.net/detail/BIM-473654
American Medical Association (AMA)
Antunes, Ricardo F.& Kaski, Juan Carlos& Dumitriu, Ingrid E.. The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis. Journal of Biomedicine and Biotechnology. 2011. Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-473654
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473654