The Association between Primary Endometrioid Carcinoma of the Ovary and Synchronous Malignancy of the Endometrium
Joint Authors
Vooijs, G. Peter
van Niekerk, Catharina C.
Bulten, Johan
Verbeek, André L. M.
Source
Obstetrics and Gynecology International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
Ovarian and endometrial cancers coincide rather frequently in the same patient.
Few data are available on the involvement of the specific morphological subtypes.
To identify histological pathways in the synchronous occurrence, a population-based study was performed in The Netherlands.
Methods.
Using the national pathology database (PALGA) information of ovarian cancers and of earlier or later cancer in the endometrium was obtained.
5366 Patients were identified with primary malignant epithelial or borderline malignancy.
Results.
In 157 cases (2.9%) a new primary malignancy in the endometrium was diagnosed (146 within 1 year).
The ratio of observed versus expected number of synchronous malignancy in the endometrium was estimated at 3.6 (95% CI: 2.7–4.7).
Among 460 ovarian endometrioid carcinoma patients 53 cases showed a second primary endometrial cancer; 40 out of these 53 cases (75.5%) showed at both organ sites an endometrioid adenocarcinoma.
Conclusion.
These findings suggest an important role for the endometrioid subtype and prompt to mechanism-based studies incorporating molecular techniques.
American Psychological Association (APA)
van Niekerk, Catharina C.& Bulten, Johan& Vooijs, G. Peter& Verbeek, André L. M.. 2009. The Association between Primary Endometrioid Carcinoma of the Ovary and Synchronous Malignancy of the Endometrium. Obstetrics and Gynecology International،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-473706
Modern Language Association (MLA)
van Niekerk, Catharina C.…[et al.]. The Association between Primary Endometrioid Carcinoma of the Ovary and Synchronous Malignancy of the Endometrium. Obstetrics and Gynecology International No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-473706
American Medical Association (AMA)
van Niekerk, Catharina C.& Bulten, Johan& Vooijs, G. Peter& Verbeek, André L. M.. The Association between Primary Endometrioid Carcinoma of the Ovary and Synchronous Malignancy of the Endometrium. Obstetrics and Gynecology International. 2009. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-473706
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473706