Acute Respiratory Distress Syndrome and Hepatotoxicity Associated with Single Dose Nitrofurantoin Use

Abstract EN

Nitrofurantoin is a synthetic nitrofuran compound.

It is generally used in urinary tract infections, either alone or in combination with other antibiotics.

A number of adverse effects may develop in different body systems during nitrofurantoin treatment; however, concomitant pulmonary and hepatotoxicity are rare.

In this paper, we present a case of acute respiratory distress syndrome and hepatotoxicity following administration of a single dose of nitrofurantoin.