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The MATCHIT Automaton : Exploiting Compartmentalization for the Synthesis of Branched Polymers
Joint Authors
Sorek, Daniel
Weyland, Mathias S.
Lancet, Doron
Füchslin, Rudolf M.
Hadorn, Maik
Rasmussen, Steen
Fellermann, Harold
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We propose an automaton, a theoretical framework that demonstrates how to improve the yield of the synthesis of branched chemical polymer reactions.
This is achieved by separating substeps of the path of synthesis into compartments.
We use chemical containers (chemtainers) to carry the substances through a sequence of fixed successive compartments.
We describe the automaton in mathematical terms and show how it can be configured automatically in order to synthesize a given branched polymer target.
The algorithm we present finds an optimal path of synthesis in linear time.
We discuss how the automaton models compartmentalized structures found in cells, such as the endoplasmic reticulum and the Golgi apparatus, and we show how this compartmentalization can be exploited for the synthesis of branched polymers such as oligosaccharides.
Lastly, we show examples of artificial branched polymers and discuss how the automaton can be configured to synthesize them with maximal yield.
American Psychological Association (APA)
Weyland, Mathias S.& Fellermann, Harold& Hadorn, Maik& Sorek, Daniel& Lancet, Doron& Rasmussen, Steen…[et al.]. 2013. The MATCHIT Automaton : Exploiting Compartmentalization for the Synthesis of Branched Polymers. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-473818
Modern Language Association (MLA)
Weyland, Mathias S.…[et al.]. The MATCHIT Automaton : Exploiting Compartmentalization for the Synthesis of Branched Polymers. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-473818
American Medical Association (AMA)
Weyland, Mathias S.& Fellermann, Harold& Hadorn, Maik& Sorek, Daniel& Lancet, Doron& Rasmussen, Steen…[et al.]. The MATCHIT Automaton : Exploiting Compartmentalization for the Synthesis of Branched Polymers. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-473818
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473818