Deconvolution-Based CT and MR Brain Perfusion Measurement : Theoretical Model Revisited and Practical Implementation Details
Joint Authors
Fieselmann, Andreas
Ganguly, Arundhuti
Fahrig, Rebecca
Kowarschik, Markus
Hornegger, Joachim
Source
International Journal of Biomedical Imaging
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-28
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
Deconvolution-based analysis of CT and MR brain perfusion data is widely used in clinical practice and it is still a topic of ongoing research activities.
In this paper, we present a comprehensive derivation and explanation of the underlying physiological model for intravascular tracer systems.
We also discuss practical details that are needed to properly implement algorithms for perfusion analysis.
Our description of the practical computer implementation is focused on the most frequently employed algebraic deconvolution methods based on the singular value decomposition.
In particular, we further discuss the need for regularization in order to obtain physiologically reasonable results.
We include an overview of relevant preprocessing steps and provide numerous references to the literature.
We cover both CT and MR brain perfusion imaging in this paper because they share many common aspects.
The combination of both the theoretical as well as the practical aspects of perfusion analysis explicitly emphasizes the simplifications to the underlying physiological model that are necessary in order to apply it to measured data acquired with current CT and MR scanners.
American Psychological Association (APA)
Fieselmann, Andreas& Kowarschik, Markus& Ganguly, Arundhuti& Hornegger, Joachim& Fahrig, Rebecca. 2011. Deconvolution-Based CT and MR Brain Perfusion Measurement : Theoretical Model Revisited and Practical Implementation Details. International Journal of Biomedical Imaging،Vol. 2011, no. 2011, pp.1-20.
https://search.emarefa.net/detail/BIM-473828
Modern Language Association (MLA)
Fieselmann, Andreas…[et al.]. Deconvolution-Based CT and MR Brain Perfusion Measurement : Theoretical Model Revisited and Practical Implementation Details. International Journal of Biomedical Imaging No. 2011 (2011), pp.1-20.
https://search.emarefa.net/detail/BIM-473828
American Medical Association (AMA)
Fieselmann, Andreas& Kowarschik, Markus& Ganguly, Arundhuti& Hornegger, Joachim& Fahrig, Rebecca. Deconvolution-Based CT and MR Brain Perfusion Measurement : Theoretical Model Revisited and Practical Implementation Details. International Journal of Biomedical Imaging. 2011. Vol. 2011, no. 2011, pp.1-20.
https://search.emarefa.net/detail/BIM-473828
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473828