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Sleep Duration and Breast Cancer Phenotype
Joint Authors
Khawaja, Ali
Rao, Santosh
Li, Li
Thompson, Cheryl L.
Source
Journal of Cancer Epidemiology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Emerging evidence suggests that short sleep is associated with an increased risk of cancer; however, little has been done to study the role of sleep on tumor characteristics.
In this study, we evaluated the relationship between sleep duration and tumor phenotype in 972 breast cancer patients.
Sleep duration was inversely associated with tumor grade (univariate P=0.032), particularly in postmenopausal women (univariate P=0.018).
This association did not reach statistical significance after adjustments for age, race, body mass index, hormone replacement therapy use, alcohol consumption, smoking, and physical activity in the entire study sample (P=0.052), but it remained statistically significant (P=0.049) among post-menopausal patients.
We did not observe a statistically significant association between sleep duration and stage at diagnosis, ER, or HER2 receptor status.
These results present a modest association between short duration of sleep and higher grade breast cancer in post-menopausal women.
Further work needs to be done to validate these findings.
American Psychological Association (APA)
Khawaja, Ali& Rao, Santosh& Li, Li& Thompson, Cheryl L.. 2013. Sleep Duration and Breast Cancer Phenotype. Journal of Cancer Epidemiology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-473857
Modern Language Association (MLA)
Khawaja, Ali…[et al.]. Sleep Duration and Breast Cancer Phenotype. Journal of Cancer Epidemiology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-473857
American Medical Association (AMA)
Khawaja, Ali& Rao, Santosh& Li, Li& Thompson, Cheryl L.. Sleep Duration and Breast Cancer Phenotype. Journal of Cancer Epidemiology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-473857
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473857