Role of Mucosal Inflammation in Eosinophilic Esophagitis : Review of the Literature
Joint Authors
Mustacchia, Paul J.
Frieri, Marianne
Shahzad, Ghulamullah
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-11-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Eosinophilic esophagitis (EE) is increasingly recognized in adults.
It is an inflammatory disease of the esophageal mucosa, with variable presentation, unresponsive to acid suppression therapy.
The diagnosis requires histological confirmation of intense eosinophilic infiltration on esophageal biopsy specimen, however exact criteria required to make a diagnosis of EE is still being debated and a clear differentiation from gastroesophageal reflux disease (GERD) is important.
Allergen elimination or anti-inflammatory therapy may be effective in such patients.
The imperfect diagnostic criteria for EE mandate an understanding of the immunology and the pathophysiology of the disease.
It may facilitate the introduction of novel treatment modalities in an individual unresponsive to acid suppression therapy.
This paper describes basic elements of the immune-mediated injury to the esophageal mucosa and management aspects to provide a better understanding of the condition.
American Psychological Association (APA)
Shahzad, Ghulamullah& Mustacchia, Paul J.& Frieri, Marianne. 2010. Role of Mucosal Inflammation in Eosinophilic Esophagitis : Review of the Literature. ISRN Gastroenterology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-473870
Modern Language Association (MLA)
Shahzad, Ghulamullah…[et al.]. Role of Mucosal Inflammation in Eosinophilic Esophagitis : Review of the Literature. ISRN Gastroenterology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-473870
American Medical Association (AMA)
Shahzad, Ghulamullah& Mustacchia, Paul J.& Frieri, Marianne. Role of Mucosal Inflammation in Eosinophilic Esophagitis : Review of the Literature. ISRN Gastroenterology. 2010. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-473870
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473870