Improved Diabetes Control and Pancreatic Function in a Type 2 Diabetic after Omeprazole Administration
Joint Authors
Mefford, I. N.
Mefford, J. T.
Burris, C. A.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-14
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A 43-year-old man with type 2 diabetes, opposed to insulin use and poorly responsive to oral agents added sequentially over 6 years, was placed on 40 mg omeprazole twice daily.
A linear decline in daily fasting blood glucose was observed over the first two-month treatment, and his hemoglobin A1c was reduced from 11.9% to 8.2%, then sustained at 8.1% after four months.
Glucose, insulin, and C-peptide response to a 2-hour glucose tolerance test were consistently improved across this time period, and calculated beta-cell mass increased by 67%.
We believe these responses are consistent with activation or neogenesis of pancreatic beta cells, possibly through a gastrin-mediated mechanism.
American Psychological Association (APA)
Mefford, I. N.& Mefford, J. T.& Burris, C. A.. 2012. Improved Diabetes Control and Pancreatic Function in a Type 2 Diabetic after Omeprazole Administration. Case Reports in Endocrinology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-473911
Modern Language Association (MLA)
Mefford, I. N.…[et al.]. Improved Diabetes Control and Pancreatic Function in a Type 2 Diabetic after Omeprazole Administration. Case Reports in Endocrinology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-473911
American Medical Association (AMA)
Mefford, I. N.& Mefford, J. T.& Burris, C. A.. Improved Diabetes Control and Pancreatic Function in a Type 2 Diabetic after Omeprazole Administration. Case Reports in Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-473911
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473911