GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach
Joint Authors
Petignat, Patrick
Cohen, Marie
Delie, Florence
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Glucose-regulated protein of 78 kD (GRP78) is a chaperone protein mainly located in the endoplasmic reticulum (ER).
This protein is normally present at low levels in adult cells but its expression is triggered by ER stress including glucose deprivation and hypoxia.
In tumor cells, it is overexpressed with fraction of protein found at the cell surface.
This paper presents the physiology of GRP78 in the context of ovarian cancer and its potential use as drug delivery systems targeting ovarian cancer cell.
American Psychological Association (APA)
Delie, Florence& Petignat, Patrick& Cohen, Marie. 2012. GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach. Journal of Oncology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-473912
Modern Language Association (MLA)
Delie, Florence…[et al.]. GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach. Journal of Oncology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-473912
American Medical Association (AMA)
Delie, Florence& Petignat, Patrick& Cohen, Marie. GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-473912
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473912