Stem Cell-Based Therapies for Ischemic Stroke
Joint Authors
Zhou, Huchuan
Hao, Lei
Zhang, Yubo
Tian, Hong
Liu, Lei
Zou, Zhongmin
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-26
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
In recent years, stem cell-based approaches have attracted more attention from scientists and clinicians due to their possible therapeutical effect on stroke.
Animal studies have demonstrated that the beneficial effects of stem cells including embryonic stem cells (ESCs), inducible pluripotent stem cells (iPSCs), neural stem cells (NSCs), and mesenchymal stem cell (MSCs) might be due to cell replacement, neuroprotection, endogenous neurogenesis, angiogenesis, and modulation on inflammation and immune response.
Although several clinical studies have shown the high efficiency and safety of stem cell in stroke management, mainly MSCs, some issues regarding to cell homing, survival, tracking, safety, and optimal cell transplantation protocol, such as cell dose and time window, should be addressed.
Undoubtably, stem cell-based gene therapy represents a novel potential therapeutic strategy for stroke in future.
American Psychological Association (APA)
Hao, Lei& Zou, Zhongmin& Tian, Hong& Zhang, Yubo& Zhou, Huchuan& Liu, Lei. 2014. Stem Cell-Based Therapies for Ischemic Stroke. BioMed Research International،Vol. 2014, no. 2014, pp.1-17.
https://search.emarefa.net/detail/BIM-473921
Modern Language Association (MLA)
Hao, Lei…[et al.]. Stem Cell-Based Therapies for Ischemic Stroke. BioMed Research International No. 2014 (2014), pp.1-17.
https://search.emarefa.net/detail/BIM-473921
American Medical Association (AMA)
Hao, Lei& Zou, Zhongmin& Tian, Hong& Zhang, Yubo& Zhou, Huchuan& Liu, Lei. Stem Cell-Based Therapies for Ischemic Stroke. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-17.
https://search.emarefa.net/detail/BIM-473921
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473921