Factors Influencing the Outcome of Patients with Incidental Papillary Thyroid Microcarcinoma
Joint Authors
Larrañaga, Alejandra
Fluiters, Enrique
Mantinan, Beatriz
Garcia-Mayor, Ricardo V.
Rego-Iraeta, Antonia
Sánchez-Sobrino, Paula
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To analyze some factors that could influence the outcome of patients with PTMC.
Material and Methods.
This is a longitudinal observational study.
All patients diagnosed and treated for papillary thyroid microcarcinoma at the University Hospital of Vigo, between January 1994 and December 2003, were included in the present study.
Demographic characteristics, tumour characteristics, TNM stage, rate of recurrence, and treatment with 131I were the study variables.
Results.
Ninety-one patients (75 females) with an average age of 47.7±13.4 years, range 19–81, were studied.
Initial tumour staging was T1 in 90 patients and T4a in 1 case.
Initial lymph node involvement was present in 4 cases (4.4%).
We only found one case with distant metastases at diagnosis.
Postsurgical evaluation of thyroid specimens revealed that 28 (30.7%) tumours were multifocal.
The average size of the tumour was 0.44±0.25 cm, range 0.1–1.
Univariate analysis reveals a statistically significant association between tumour multifocality and postsurgical 131I therapy with the recurrence rate.
In the multivariate analysis only multifocality (P=0.037, HR 5.7) was a significant risk factor for the recurrence rate.
Conclusions.
Our results indicate that tumour multifocality is an independent predictor of relapse but neither the tumour size nor postsurgical 131I therapy.
American Psychological Association (APA)
Mantinan, Beatriz& Rego-Iraeta, Antonia& Larrañaga, Alejandra& Fluiters, Enrique& Sánchez-Sobrino, Paula& Garcia-Mayor, Ricardo V.. 2012. Factors Influencing the Outcome of Patients with Incidental Papillary Thyroid Microcarcinoma. Journal of Thyroid Research،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-473984
Modern Language Association (MLA)
Mantinan, Beatriz…[et al.]. Factors Influencing the Outcome of Patients with Incidental Papillary Thyroid Microcarcinoma. Journal of Thyroid Research No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-473984
American Medical Association (AMA)
Mantinan, Beatriz& Rego-Iraeta, Antonia& Larrañaga, Alejandra& Fluiters, Enrique& Sánchez-Sobrino, Paula& Garcia-Mayor, Ricardo V.. Factors Influencing the Outcome of Patients with Incidental Papillary Thyroid Microcarcinoma. Journal of Thyroid Research. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-473984
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-473984