Scattering Coefficients of Mice Organs Categorized Pathologically by Spectral Domain Optical Coherence Tomography

Abstract EN

Differences in tissue density cause a variety of scattering coefficients.

To quantify optical coherence tomography (OCT) images for diagnosis, the tissue's scattering coefficient is estimated by curve fitting the OCT signals to a confocal single backscattering mode.

The results from a group of 30 mice show that the scattering coefficients of bone, skin, liver, brain, testis, and spleen can be categorized into three groups: a scattering coefficient between 1.947 and 2.134 mm−1: bone and skin; a scattering coefficient between 1.303 and 1.461 mm−1: liver and brain; a scattering coefficient between 0.523 and 0.634 mm−1: testis and spleen.

The results indicate that the scattering coefficient is tissue specific and could be used in tissue diagnosis.