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Differences in Upgrading of Prostate Cancer in Prostatectomies between Community and Academic Practices
Joint Authors
Lin, Daniel W.
Ellis, William J.
Gottsch, Henry P.
True, Lawrence D.
Wright, Jonathan L.
Lee, Franklin C.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To determine whether initial biopsy performed by community or academic urologists affected rates of Gleason upgrading at a tertiary referral center.
Gleason upgrading from biopsy to radical prostatectomy (RP) is an important event as treatment decisions are made based on the biopsy score.
Materials and Methods.
We identified men undergoing RP for Gleason 3+3 or 3+4 disease at a tertiary care academic center.
Biopsy performed in the community was centrally reviewed at the academic center.
Multivariate logistic regression was used to determine factors associated with Gleason upgrading.
Results.
We reviewed 1,348 men.
There was no difference in upgrading whether the biopsy was performed at academic or community sites (OR 0.9, 95% CI 0.7–1.2).
Increased risk of upgrading was seen in those with >1 positive core, older men, and those with higher PSAs.
Secondary pattern 4 and larger prostate size were associated with a reduction in risk of upgrading.
Compared to the smallest quartile of prostate size (<35 g), those in the highest quartile (>56 g) had a 49% reduction in risk of upgrading (OR 0.51, 95% CI 0.3–0.7).
Conclusion.
There was no difference in upgrading between where the biopsy was performed and community and academic urologists.
American Psychological Association (APA)
Lee, Franklin C.& Gottsch, Henry P.& Ellis, William J.& True, Lawrence D.& Lin, Daniel W.& Wright, Jonathan L.. 2013. Differences in Upgrading of Prostate Cancer in Prostatectomies between Community and Academic Practices. Advances in Urology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-474114
Modern Language Association (MLA)
Lee, Franklin C.…[et al.]. Differences in Upgrading of Prostate Cancer in Prostatectomies between Community and Academic Practices. Advances in Urology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-474114
American Medical Association (AMA)
Lee, Franklin C.& Gottsch, Henry P.& Ellis, William J.& True, Lawrence D.& Lin, Daniel W.& Wright, Jonathan L.. Differences in Upgrading of Prostate Cancer in Prostatectomies between Community and Academic Practices. Advances in Urology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-474114
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474114