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Corneal Epithelial Wound Healing Promoted by Verbascoside-Based Liposomal Eyedrops
Joint Authors
Filippelli, Mariaelena
Guerra, Germano
Mosca, Monica
Cinelli, Mariapia
Vizzarri, Francesco
Costagliola, Ciro
Giorgio, Dario
Ambrosone, Luigi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Different liposomal formulations were prepared to identify those capable of forming eyedrops for corneal diseases.
Liposomes with neutral or slightly positive surface charge interact very well with the cornea.
Then these formulations were loaded with verbascoside to heal a burn of corneal epithelium induced by alkali.
The cornea surface affected involved in wound was monitored as a function of time.
Experimental results were modeled by balance equation between the rate of healing, due to the flow of phenylpropanoid, and growth of the wound.
The results indicate a latency time of only three hours and furthermore the corneal epithelium heals in 48 hours.
Thus, the topical administration of verbascoside appears to reduce the action time of cells, as verified by histochemical and immunofluorescence assays.
American Psychological Association (APA)
Ambrosone, Luigi& Guerra, Germano& Cinelli, Mariapia& Filippelli, Mariaelena& Mosca, Monica& Vizzarri, Francesco…[et al.]. 2014. Corneal Epithelial Wound Healing Promoted by Verbascoside-Based Liposomal Eyedrops. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-474154
Modern Language Association (MLA)
Ambrosone, Luigi…[et al.]. Corneal Epithelial Wound Healing Promoted by Verbascoside-Based Liposomal Eyedrops. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-474154
American Medical Association (AMA)
Ambrosone, Luigi& Guerra, Germano& Cinelli, Mariapia& Filippelli, Mariaelena& Mosca, Monica& Vizzarri, Francesco…[et al.]. Corneal Epithelial Wound Healing Promoted by Verbascoside-Based Liposomal Eyedrops. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-474154
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474154