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Clean Procedure and DFT Study for the Synthesis of 2-Amino-3-ethoxycarbonyl-4-(aryl)-4H-pyrano-[3,2-c]-chromene-5-ones Derivatives : A Novel Class of Potential Antimicrobial and Antioxidant Agents
Joint Authors
Ben Said, R.
Hamdi, N.
Medyouni, R.
al-Ayed, A. S.
Zagrouba, Fethi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
2-Amino-3-ethoxycarbonyl-4-(aryl)-4H-pyrano-[3,2-c]-chromene-5-ones 5 is synthesized by the two-component reaction of 4-hydroxycouamrin with ethyl-2-cyano-3-(aryl) acrylate 3.
The structures of the obtained compounds are confirmed by analytical IR, 1H, and 13C-NMR spectra to elucidate the different positions of protons and carbons and as well as theoretic studies (DFT/B3LYP).
All the newly synthesized compounds are screened for their antibacterial.
Furthermore, these compounds showed antioxidant activities of different extents with respect to individual compounds as well as to the antioxidant methods.
The compounds 5a–e were found to be the most active antioxidant in the series then Trolox, which makes the investigated complexes a promising new class of antibacterial activity compounds.
American Psychological Association (APA)
Medyouni, R.& Hamdi, N.& Ben Said, R.& al-Ayed, A. S.& Zagrouba, Fethi. 2012. Clean Procedure and DFT Study for the Synthesis of 2-Amino-3-ethoxycarbonyl-4-(aryl)-4H-pyrano-[3,2-c]-chromene-5-ones Derivatives : A Novel Class of Potential Antimicrobial and Antioxidant Agents. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-474249
Modern Language Association (MLA)
Medyouni, R.…[et al.]. Clean Procedure and DFT Study for the Synthesis of 2-Amino-3-ethoxycarbonyl-4-(aryl)-4H-pyrano-[3,2-c]-chromene-5-ones Derivatives : A Novel Class of Potential Antimicrobial and Antioxidant Agents. Journal of Chemistry No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-474249
American Medical Association (AMA)
Medyouni, R.& Hamdi, N.& Ben Said, R.& al-Ayed, A. S.& Zagrouba, Fethi. Clean Procedure and DFT Study for the Synthesis of 2-Amino-3-ethoxycarbonyl-4-(aryl)-4H-pyrano-[3,2-c]-chromene-5-ones Derivatives : A Novel Class of Potential Antimicrobial and Antioxidant Agents. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-474249
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474249