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Unsupervised Learning in Detection of Gene Transfer
Joint Authors
Poptsova, M.S.
Zhaxybayeva, O.
Gogarten, J. Peter
Nahar, N.
Hamel, L.
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-04-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The tree representation as a model for organismal evolution has been in use since before Darwin.
However, with the recent unprecedented access to biomolecular data, it has been discovered that, especially in the microbial world, individual genes making up the genome of an organism give rise to different and sometimes conflicting evolutionary tree topologies.
This discovery calls into question the notion of a single evolutionary tree for an organism and gives rise to the notion of an evolutionary consensus tree based on the evolutionary patterns of the majority of genes in a genome embedded in a network of gene histories.
Here, we discuss an approach to the analysis of genomic data of multiple genomes using bipartition spectral analysis and unsupervised learning.
An interesting observation is that genes within genomes that have evolutionary tree topologies, which are in substantial conflict with the evolutionary consensus tree of an organism, point to possible horizontal gene transfer events which often delineate significant evolutionary events.
American Psychological Association (APA)
Hamel, L.& Nahar, N.& Poptsova, M.S.& Zhaxybayeva, O.& Gogarten, J. Peter. 2008. Unsupervised Learning in Detection of Gene Transfer. Journal of Biomedicine and Biotechnology،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-474255
Modern Language Association (MLA)
Hamel, L.…[et al.]. Unsupervised Learning in Detection of Gene Transfer. Journal of Biomedicine and Biotechnology No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-474255
American Medical Association (AMA)
Hamel, L.& Nahar, N.& Poptsova, M.S.& Zhaxybayeva, O.& Gogarten, J. Peter. Unsupervised Learning in Detection of Gene Transfer. Journal of Biomedicine and Biotechnology. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-474255
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474255