Optical Coherence Tomography in Multiple Sclerosis and Neuromyelitis Optica : An Update
Joint Authors
Manzano, Beatriz
Muñoz, Silvia
Contreras, Inés
Rebolleda, Gema
Oreja-Guevara, Celia
Noval, Susana
Source
Multiple Sclerosis International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-02
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Optical coherence tomography (OCT) uses light interference patterns to produce a cross-sectional image of the retina.
It is capable of measuring the unmyelinated axons of the retinal ganglionar cells as they converge on the optic disc.
In a disease like multiple sclerosis (MS), in which axonal loss has been identified as an important cause of sustained disability, it may prove an invaluable tool.
OCT has demonstrated that axonal loss occurs after each episode of optic neuritis and that the degree of axonal loss is correlated to visual outcomes.
Furthermore, axonal loss occurs in MS even in the absence of inflammatory episodes, and the degree of this loss is correlated with the duration of the disease process, with more thinning as the disease advances and in progressive forms.
Thus, OCT retinal nerve fiber layer measurements may represent an objective outcome measure with which to evaluate the effect of treatment.
American Psychological Association (APA)
Noval, Susana& Contreras, Inés& Muñoz, Silvia& Oreja-Guevara, Celia& Manzano, Beatriz& Rebolleda, Gema. 2011. Optical Coherence Tomography in Multiple Sclerosis and Neuromyelitis Optica : An Update. Multiple Sclerosis International،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-474264
Modern Language Association (MLA)
Noval, Susana…[et al.]. Optical Coherence Tomography in Multiple Sclerosis and Neuromyelitis Optica : An Update. Multiple Sclerosis International No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-474264
American Medical Association (AMA)
Noval, Susana& Contreras, Inés& Muñoz, Silvia& Oreja-Guevara, Celia& Manzano, Beatriz& Rebolleda, Gema. Optical Coherence Tomography in Multiple Sclerosis and Neuromyelitis Optica : An Update. Multiple Sclerosis International. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-474264
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474264