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Antioxidant Therapies for Alzheimer's Disease
Joint Authors
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-25
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Alzheimer’s disease (AD) is the most common neurodegenerative disease featuring progressive impairments in memory, cognition, and behavior and ultimately leads to death.
The histopathological changes of Alzheimer’s disease include neuronal and synaptic loss, formation of extracellular senile plaques and intracellular neurofibrillary tangles in brain.
Multiple lines of evidence indicate that oxidative stress not only strongly participates in an early stage of Alzheimer’s disease prior to cytopathology, but plays an important role in inducing and activating multiple cell signaling pathways that contribute to the lesion formations of toxic substances and then promotes the development of Alzheimer’s disease.
Many years of studies show that antioxidant therapies have enjoyed general success in preclinical studies.
Therefore, this paper mainly focuses on the recent developments of common used antioxidant therapies for Alzheimer’s disease and thus provides indications for future potential antioxidant therapeutic strategies of neurodegenerative diseases.
American Psychological Association (APA)
Feng, Ye& Wang, Xiaochuan. 2012. Antioxidant Therapies for Alzheimer's Disease. Oxidative Medicine and Cellular Longevity،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-474273
Modern Language Association (MLA)
Feng, Ye& Wang, Xiaochuan. Antioxidant Therapies for Alzheimer's Disease. Oxidative Medicine and Cellular Longevity No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-474273
American Medical Association (AMA)
Feng, Ye& Wang, Xiaochuan. Antioxidant Therapies for Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-474273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474273