Some Observations on Carbon Nanotubes Susceptibility to Cell Phagocytosis
Joint Authors
Fraczek-Szczypta, Aneta
Blazewicz, Stanislaw
Menaszek, Elzbieta
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
The aim of this study was to assess the influence of different types of carbon nanotubes (CNTs) on cell phagocytosis.
Three kinds of carbon nanotubes: single-walled carbon nanohorns (SWCNHs), multiwalled carbon nanotubes (MWCNTs), and ultra-long single-walled carbon nanotubes (ULSWCNTs) before and after additional chemical functionalization were seeded with macrophage cell culture.
Prior to biological testing, the CNTs were subjected to dispersion process with the use of phosphate buffered solution (PBS) and PBS containing surfactant (Tween 20) or dimethyl sulfoxide (DMSO).
The results indicate that the cells interaction with an individual nanotube is entirely different as compared to CNTs in the form of aggregate.
The presence of the surfactant favors the CNTs dispersion in culture media and facilitates phagocytosis process, while it has disadvantageous influence on cells morphology.
The cells phagocytosis is a more effective for MWCNTs and SWCNHs after their chemical functionalization.
Moreover, these nanotubes were well dispersed in culture media without using DMSO or surfactant.
The functionalized carbon nanotubes were easily dispersed in pure PBS and seeded with cells.
American Psychological Association (APA)
Fraczek-Szczypta, Aneta& Menaszek, Elzbieta& Blazewicz, Stanislaw. 2011. Some Observations on Carbon Nanotubes Susceptibility to Cell Phagocytosis. Journal of Nanomaterials،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-474334
Modern Language Association (MLA)
Fraczek-Szczypta, Aneta…[et al.]. Some Observations on Carbon Nanotubes Susceptibility to Cell Phagocytosis. Journal of Nanomaterials No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-474334
American Medical Association (AMA)
Fraczek-Szczypta, Aneta& Menaszek, Elzbieta& Blazewicz, Stanislaw. Some Observations on Carbon Nanotubes Susceptibility to Cell Phagocytosis. Journal of Nanomaterials. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-474334
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474334