Cystitis : From Urothelial Cell Biology to Clinical Applications
Joint Authors
Lee, Gilho
Zupančič, Daša
Romih, Rok
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Cystitis is a urinary bladder disease with many causes and symptoms.
The severity of cystitis ranges from mild lower abdominal discomfort to life-threatening haemorrhagic cystitis.
The course of disease is often chronic or recurrent.
Although cystitis represents huge economical and medical burden throughout the world and in many cases treatments are ineffective, the mechanisms of its origin and development as well as measures for effective treatment are still poorly understood.
However, many studies have demonstrated that urothelial dysfunction plays a crucial role.
In the present review we first discuss fundamental issues of urothelial cell biology, which is the core for comprehension of cystitis.
Then we focus on many forms of cystitis, its current treatments, and advances in its research.
Additionally we review haemorrhagic cystitis with one of the leading causative agents being chemotherapeutic drug cyclophosphamide and summarise its management strategies.
At the end we describe an excellent and widely used animal model of cyclophosphamide induced cystitis, which gives researches the opportunity to get a better insight into the mechanisms involved and possibility to develop new therapy approaches.
American Psychological Association (APA)
Lee, Gilho& Romih, Rok& Zupančič, Daša. 2014. Cystitis : From Urothelial Cell Biology to Clinical Applications. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-474337
Modern Language Association (MLA)
Lee, Gilho…[et al.]. Cystitis : From Urothelial Cell Biology to Clinical Applications. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-474337
American Medical Association (AMA)
Lee, Gilho& Romih, Rok& Zupančič, Daša. Cystitis : From Urothelial Cell Biology to Clinical Applications. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-474337
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474337