Treatment of Chronic Hepatitis C in a Patient Affected by Systemic Sclerosis
Joint Authors
Montagna, Benedetta
Villani, Laura
Amatu, Alessio
Bernardo, Giovanni
Poggi, Guido
Sottotetti, Federico
Tagliaferri, Barbara
Source
Gastroenterology Research and Practice
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-11-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The currently recommended treatment for patients infected with hepatitis C virus (HCV) is pegilated interferon α (IFN α) plus ribavirin.
Despite the numerous benefits of this therapy, there is an increasing concern regarding his tolerance.
Among the most common side effects, interferon may trigger the onset or exacerbation of autoimmune diseases.
When chronic hepatitis C coexists with an autoimmune disorder, it is not clear whether using interferon is better than avoiding it.
We evaluated the disease state of a 55-year old female affected by sistemic sclerosis (SSc), during and after therapy with IFNα pegilated plus ribavirin for chronic HCV infection.
We were worried about the potential worsening of the autoimmune disease during the therapy, but we were confident that we would give our patient a short course of peginterferon and ribavirin.
A mild, asymptomatic worsening of lung SSc was observed during IFN administration, without life threatening symptoms.
After 24 months follow up we observed the maintenance of the virological response and a good control of the rheumatological disease.
Thus, in liver disease at high risk of progression and concomitant SSc, the antiviral therapy with IFNα is a feasible approach.
American Psychological Association (APA)
Poggi, Guido& Villani, Laura& Sottotetti, Federico& Tagliaferri, Barbara& Montagna, Benedetta& Amatu, Alessio…[et al.]. 2009. Treatment of Chronic Hepatitis C in a Patient Affected by Systemic Sclerosis. Gastroenterology Research and Practice،Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-474524
Modern Language Association (MLA)
Poggi, Guido…[et al.]. Treatment of Chronic Hepatitis C in a Patient Affected by Systemic Sclerosis. Gastroenterology Research and Practice No. 2009 (2009), pp.1-5.
https://search.emarefa.net/detail/BIM-474524
American Medical Association (AMA)
Poggi, Guido& Villani, Laura& Sottotetti, Federico& Tagliaferri, Barbara& Montagna, Benedetta& Amatu, Alessio…[et al.]. Treatment of Chronic Hepatitis C in a Patient Affected by Systemic Sclerosis. Gastroenterology Research and Practice. 2009. Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-474524
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474524