Quantitative Cartilage Imaging in Knee Osteoarthritis
Joint Authors
Eckstein, Felix
Wirth, Wolfgang
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-08
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Quantitative measures of cartilage morphology (i.e., thickness) represent potentially powerful surrogate endpoints in osteoarthritis (OA).
These can be used to identify risk factors of structural disease progression and can facilitate the clinical efficacy testing of structure modifying drugs in OA.
This paper focuses on quantitative imaging of articular cartilage morphology in the knee, and will specifically deal with different cartilage morphology outcome variables and regions of interest, the relative performance and relationship between cartilage morphology measures, reference values for MRI-based knee cartilage morphometry, imaging protocols for measurement of cartilage morphology (including those used in the Osteoarthritis Initiative), sensitivity to change observed in knee OA, spatial patterns of cartilage loss as derived by subregional analysis, comparison of MRI changes with radiographic changes, risk factors of MRI-based cartilage loss in knee OA, the correlation of MRI-based cartilage loss with clinical outcomes, treatment response in knee OA, and future directions of the field.
American Psychological Association (APA)
Eckstein, Felix& Wirth, Wolfgang. 2010. Quantitative Cartilage Imaging in Knee Osteoarthritis. Arthritis،Vol. 2011, no. 2011, pp.1-19.
https://search.emarefa.net/detail/BIM-474545
Modern Language Association (MLA)
Eckstein, Felix& Wirth, Wolfgang. Quantitative Cartilage Imaging in Knee Osteoarthritis. Arthritis No. 2011 (2011), pp.1-19.
https://search.emarefa.net/detail/BIM-474545
American Medical Association (AMA)
Eckstein, Felix& Wirth, Wolfgang. Quantitative Cartilage Imaging in Knee Osteoarthritis. Arthritis. 2010. Vol. 2011, no. 2011, pp.1-19.
https://search.emarefa.net/detail/BIM-474545
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474545