Enzyme-Mediated Ring-Opening Polymerization of Pentadecalactone to Obtain Biodegradable Polymer for Fabrication of Scaffolds for Bone Tissue Engineering

Joint Authors

Litvinchuk, E. N.
Tennikova, T. B.
Korzhikov, V. A.
Gusevskaya, K. V.
Vlakh, E. G.

Source

International Journal of Polymer Science

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-09-25

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Physics

Abstract EN

The optimization of enzyme-mediated polymerization of pentadecalactone (PDL) was performed to obtain macromolecular products suitable for generation of 3D cell supports (scaffolds) for bone tissue engineering.

Such parameters as temperature, monomer/enzyme ratio, and monomer concentration were studied.

The maximum molecular weight of synthesized polymers was about 90,000.

Methods allowing the introduction of reactive double bonds into polypentadecalactone (polyPDL) structure were developed.

The macroporous matrices were obtained by modification of thermoinduced phase separation method.

American Psychological Association (APA)

Korzhikov, V. A.& Gusevskaya, K. V.& Litvinchuk, E. N.& Vlakh, E. G.& Tennikova, T. B.. 2013. Enzyme-Mediated Ring-Opening Polymerization of Pentadecalactone to Obtain Biodegradable Polymer for Fabrication of Scaffolds for Bone Tissue Engineering. International Journal of Polymer Science،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-474648

Modern Language Association (MLA)

Korzhikov, V. A.…[et al.]. Enzyme-Mediated Ring-Opening Polymerization of Pentadecalactone to Obtain Biodegradable Polymer for Fabrication of Scaffolds for Bone Tissue Engineering. International Journal of Polymer Science No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-474648

American Medical Association (AMA)

Korzhikov, V. A.& Gusevskaya, K. V.& Litvinchuk, E. N.& Vlakh, E. G.& Tennikova, T. B.. Enzyme-Mediated Ring-Opening Polymerization of Pentadecalactone to Obtain Biodegradable Polymer for Fabrication of Scaffolds for Bone Tissue Engineering. International Journal of Polymer Science. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-474648

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-474648