Peripartum Cardiomyopathy Presenting with Predominant Left Ventricular Diastolic Dysfunction : Efficacy of Bromocriptine
Joint Authors
Rapisardi, Gherardo
Betti, Irene
Chiodi, Leandro
Mangialavori, Giuseppe
Ballo, Piercarlo
Zuppiroli, Alfredo
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Management of patients with peripartum cardiomyopathy (PPCM) is still a major clinical problem, as only half of them or slightly more show complete recovery of left ventricular (LV) function despite conventional evidence-based treatment for heart failure.
Recent observations suggested that bromocriptine might favor recovery of LV systolic function in patients with PPCM.
However, no evidence exists regarding its effect on LV diastolic dysfunction, which is commonly observed in these patients.
Tissue Doppler (TD) is an echocardiographic technique that provides unique information on LV diastolic performance.
We report the case of a 37-year-old white woman with heart failure (NYHA class II), moderate LV systolic dysfunction (ejection fraction 35%), and severe LV diastolic dysfunction secondary to PPCM, who showed no improvement after 2 weeks of treatment with ramipril, bisoprolol, and furosemide.
At 6-week followup after addition of bromocriptine, despite persistence of LV systolic dysfunction, normalization of LV diastolic function was shown by TD, together with improvement in functional status (NYHA I).
At 18-month followup, the improvement in LV diastolic function was maintained, and normalization of systolic function was observed.
This paper might support the clinical utility of bromocriptine in patients with PPCM by suggesting a potential benefit on LV diastolic dysfunction.
American Psychological Association (APA)
Ballo, Piercarlo& Betti, Irene& Mangialavori, Giuseppe& Chiodi, Leandro& Rapisardi, Gherardo& Zuppiroli, Alfredo. 2012. Peripartum Cardiomyopathy Presenting with Predominant Left Ventricular Diastolic Dysfunction : Efficacy of Bromocriptine. Case Reports in Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-474670
Modern Language Association (MLA)
Ballo, Piercarlo…[et al.]. Peripartum Cardiomyopathy Presenting with Predominant Left Ventricular Diastolic Dysfunction : Efficacy of Bromocriptine. Case Reports in Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-474670
American Medical Association (AMA)
Ballo, Piercarlo& Betti, Irene& Mangialavori, Giuseppe& Chiodi, Leandro& Rapisardi, Gherardo& Zuppiroli, Alfredo. Peripartum Cardiomyopathy Presenting with Predominant Left Ventricular Diastolic Dysfunction : Efficacy of Bromocriptine. Case Reports in Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-474670
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474670