Beneficial Effects of Pentanema vestitum Linn. Whole Plant on the Glucose and Other Biochemical Parameters of Alloxan Induced Diabetic Rabbits
Joint Authors
Ilahi, Ikram
Khan, Murad
Khan, Nasrullah
Ali, Shujat
Asghar, Ali
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
The residents of Lower Dir and Malakand agency, Khyber Pakhtunkhwa, Pakistan, use the dry powder of whole plant of Pentanema vestitum for the treatment of asthma and diabetes.
No documented reports are available about the therapeutic action of Pentanema vestitum.
The present study was aimed to explore the antihyperglycemic effect of 70% methanol extract of Pentanema vestitum whole plant in glucose-induced nondiabetic hyperglycemic and alloxan-induced diabetic rabbits.
During this study, the effects of plant extract on the serum lipid profile, GPT, ALP, bilirubin and creatinine of diabetic rabbits were also studied.
The extract of Pentanema vestitum whole plant exhibited significant (P<0.05) antihyperglycemic activity in glucose-induced hyperglycemic rabbits.
Treatment of alloxan-induced diabetic rabbits with extract significantly (P<0.05) reduced the elevated levels of serum glucose, GPT, ALP, bilirubin and creatinine.
During the study of lipid profile, the extract proved to be antihyperlipidemic and HDL boosting in diabetic rabbit models.
From the finding of the present research, it was concluded that the 70% methanol extract of Pentanema vestitum whole plant has beneficial effects on serum levels of glucose, lipid profile, GPT, ALP, bilirubin, and creatinine of diabetic rabbits.
American Psychological Association (APA)
Ilahi, Ikram& Asghar, Ali& Ali, Shujat& Khan, Murad& Khan, Nasrullah. 2012. Beneficial Effects of Pentanema vestitum Linn. Whole Plant on the Glucose and Other Biochemical Parameters of Alloxan Induced Diabetic Rabbits. ISRN Pharmacology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-474680
Modern Language Association (MLA)
Ilahi, Ikram…[et al.]. Beneficial Effects of Pentanema vestitum Linn. Whole Plant on the Glucose and Other Biochemical Parameters of Alloxan Induced Diabetic Rabbits. ISRN Pharmacology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-474680
American Medical Association (AMA)
Ilahi, Ikram& Asghar, Ali& Ali, Shujat& Khan, Murad& Khan, Nasrullah. Beneficial Effects of Pentanema vestitum Linn. Whole Plant on the Glucose and Other Biochemical Parameters of Alloxan Induced Diabetic Rabbits. ISRN Pharmacology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-474680
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474680