Autism Spectrum Disorders : Is Mesenchymal Stem Cell Personalized Therapy the Future?
Joint Authors
Maione, Sabatino
Sapone, Anna
Siniscalco, Dario
Giordano, Catia
Antonucci, Nicola
Cirillo, Alessandra
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Autism and autism spectrum disorders (ASDs) are heterogeneous neurodevelopmental disorders.
They are enigmatic conditions that have their origins in the interaction of genes and environmental factors.
ASDs are characterized by dysfunctions in social interaction and communication skills, in addition to repetitive and stereotypic verbal and nonverbal behaviours.
Immune dysfunction has been confirmed with autistic children.
There are no defined mechanisms of pathogenesis or curative therapy presently available.
Indeed, ASDs are still untreatable.
Available treatments for autism can be divided into behavioural, nutritional, and medical approaches, although no defined standard approach exists.
Nowadays, stem cell therapy represents the great promise for the future of molecular medicine.
Among the stem cell population, mesenchymal stem cells (MSCs) show probably best potential good results in medical research.
Due to the particular immune and neural dysregulation observed in ASDs, mesenchymal stem cell transplantation could offer a unique tool to provide better resolution for this disease.
American Psychological Association (APA)
Siniscalco, Dario& Sapone, Anna& Cirillo, Alessandra& Giordano, Catia& Maione, Sabatino& Antonucci, Nicola. 2012. Autism Spectrum Disorders : Is Mesenchymal Stem Cell Personalized Therapy the Future?. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-474873
Modern Language Association (MLA)
Siniscalco, Dario…[et al.]. Autism Spectrum Disorders : Is Mesenchymal Stem Cell Personalized Therapy the Future?. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-474873
American Medical Association (AMA)
Siniscalco, Dario& Sapone, Anna& Cirillo, Alessandra& Giordano, Catia& Maione, Sabatino& Antonucci, Nicola. Autism Spectrum Disorders : Is Mesenchymal Stem Cell Personalized Therapy the Future?. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-474873
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474873