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Antireflux Endoluminal Therapies : Past and Present
Joint Authors
Source
Gastroenterology Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The basic principle of antireflux procedures employing endoscopic intervention aims to create a mechanical barrier to prevent primary pathophysiology in gastroesophageal reflux disease (GERD).
We review, highlight, and discuss the past and present status of endoluminal therapy.
Currently, there are 3 commonly employed anti-reflux endoluminal procedures: fundoplication or suturing techniques (EndoCinch, NDO, and EsophyX), intramural injection or implant techniques (enhancing lower esophageal sphincter (LES) volume and/or strengthening compliance of the LES-Enteryx and Gatekeeper), and radiofrequency ablation of LES and cardia.
EndoCinch plication requires further study and modification of technique before it can be recommended because of durability issues.
Esophynx, the transoral incisionless fundoplication, may reduce hiatal hernias and increase LES length.
Preliminary studies have shown promising reduction in symptoms and medication use but evidence concerning safety and long-term durability is still pending.
The safety issue with injection technique is the main concern as evident from the incidences of implant withdrawals after reported major adverse events.
Future research with cautious monitoring is required before any new implant material can be recommended for commercial application.
Radiofrequency ablation therapy is regaining popularity in treating refractory symptoms despite PPI use due to improved efficacy, durability, and safety after years of refinement of protocol.
American Psychological Association (APA)
Yew, Kuo Chao& Chuah, Seng-Kee. 2013. Antireflux Endoluminal Therapies : Past and Present. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-474996
Modern Language Association (MLA)
Yew, Kuo Chao& Chuah, Seng-Kee. Antireflux Endoluminal Therapies : Past and Present. Gastroenterology Research and Practice No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-474996
American Medical Association (AMA)
Yew, Kuo Chao& Chuah, Seng-Kee. Antireflux Endoluminal Therapies : Past and Present. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-474996
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-474996