Effect of Therapy by Using Advocate Spot-On Combination (Imidacloprid 10% and Moxidectin 2.5%)‎ on Subcutaneous Dirofilariosis in Dogs

Abstract EN

Dirofilaria (Nochtiella) repens is a filarioid parasite that causes subcutaneous dirofilariosis in dogs.

Adults, while localized in subcutaneous tissues, lay embryos (microfilariae (mf)) into the blood stream of dogs, which constitute a reservoir for infection of other definitive or accidental hosts as humans.

This study was carried out to assess the efficacy of spot-on combination of imidacloprid and moxidectin on microfilariaemia in naturally infected dogs.

A group of 11 dogs was monthly examined for the presence of microfilariae in peripheral blood by modified Knott's test method.

Treatment was administered monthly for 4 months.

All dogs (i.e., 100%) became negative for microfilariaemia throughout the study.

These results confirm the effect of the combination of imidacloprid and moxidectin on D.

(Nochtiella) repens.