Stereotactic Irradiation of GH-Secreting Pituitary Adenomas
Joint Authors
Scaringi, C.
Enrici, Riccardo Maurizi
Amelio, D.
Minniti, G.
Source
International Journal of Endocrinology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Radiotherapy (RT) is often employed in patients with acromegaly refractory to medical and/or surgical interventions in order to prevent tumour regrowth and normalize elevated GH and IGF-I levels.
It achieves tumour control and hormone normalization up to 90% and 70% of patients at 10–15 years.
Despite the excellent tumour control, conventional RT is associated with a potential risk of developing late toxicity, especially hypopituitarism, and its role in the management of patients with GH-secreting pituitary adenomas remains a matter of debate.
Stereotactic techniques have been developed with the aim to deliver more localized irradiation and minimize the long-term consequences of treatment, while improving its efficacy.
Stereotactic irradiation can be given in a single dose as stereotactic radiosurgery (SRS) or in multiple doses as fractionated stereotactic radiotherapy (FSRT).
We have reviewed the recent published literature on stereotactic techniques for GH-secreting pituitary tumors with the aim to define the efficacy and potential adverse effects of each of these techniques.
American Psychological Association (APA)
Minniti, G.& Scaringi, C.& Amelio, D.& Enrici, Riccardo Maurizi. 2012. Stereotactic Irradiation of GH-Secreting Pituitary Adenomas. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-475144
Modern Language Association (MLA)
Minniti, G.…[et al.]. Stereotactic Irradiation of GH-Secreting Pituitary Adenomas. International Journal of Endocrinology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-475144
American Medical Association (AMA)
Minniti, G.& Scaringi, C.& Amelio, D.& Enrici, Riccardo Maurizi. Stereotactic Irradiation of GH-Secreting Pituitary Adenomas. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-475144
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475144