Surgical Technique in Distal Pancreatectomy : A Systematic Review of Randomized Trials
Joint Authors
Čečka, Filip
Ferko, Alexander
Jon, Bohumil
Šubrt, Zdeněk
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Despite recent improvements in surgical technique, the morbidity of distal pancreatectomy remains high, with pancreatic fistula being the most significant postoperative complication.
A systematic review of randomized controlled trials (RCTs) dealing with surgical techniques in distal pancreatectomy was carried out to summarize up-to-date knowledge on this topic.
The Cochrane Central Registry of Controlled Trials, Embase, Web of Science, and Pubmed were searched for relevant articles published from 1990 to December 2013.
Ten RCTs were identified and included in the systematic review, with a total of 1286 patients being randomized (samples ranging from 41 to 450).
The reviewers were in agreement for application of the eligibility criteria for study selection.
It was not possible to carry out meta-analysis of these studies because of the heterogeneity of surgical techniques and approaches, such as varying methods of pancreas transection, reinforcement of the stump with seromuscular patch or pancreaticoenteric anastomosis, sealing with fibrin sealants and pancreatic stent placement.
Management of the pancreatic remnant after distal pancreatectomy is still a matter of debate.
The results of this systematic review are possibly biased by methodological problems in some of the included studies.
New well designed and carefully conducted RCTs must be performed to establish the optimal strategy for pancreatic remnant management after distal pancreatectomy.
American Psychological Association (APA)
Čečka, Filip& Jon, Bohumil& Šubrt, Zdeněk& Ferko, Alexander. 2014. Surgical Technique in Distal Pancreatectomy : A Systematic Review of Randomized Trials. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-475147
Modern Language Association (MLA)
Čečka, Filip…[et al.]. Surgical Technique in Distal Pancreatectomy : A Systematic Review of Randomized Trials. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-475147
American Medical Association (AMA)
Čečka, Filip& Jon, Bohumil& Šubrt, Zdeněk& Ferko, Alexander. Surgical Technique in Distal Pancreatectomy : A Systematic Review of Randomized Trials. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-475147
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475147