Liposarcoma : Molecular Genetics and Therapeutics
Joint Authors
Young, Sophie
Conyers, Rachel
Thomas, David M.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-27
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Sarcomas are a group of heterogeneous tumours with varying genetic basis.
Cytogenetic abnormalities range from distinct genomic rearrangements such as pathognomonic translocation events and common chromosomal amplification or loss, to more complex rearrangements involving multiple chromosomes.
The different subtypes of liposarcoma are spread across this spectrum and constitute an interesting tumour type for molecular review.
This paper will outline molecular pathogenesis of the three main subtypes of liposarcoma: well-differentiated/dedifferentiated, myxoid/round cell, and pleomorphic liposarcoma.
Both the molecular basis and future avenues for therapeutic intervention will be discussed.
American Psychological Association (APA)
Conyers, Rachel& Young, Sophie& Thomas, David M.. 2010. Liposarcoma : Molecular Genetics and Therapeutics. Sarcoma،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-475177
Modern Language Association (MLA)
Conyers, Rachel…[et al.]. Liposarcoma : Molecular Genetics and Therapeutics. Sarcoma No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-475177
American Medical Association (AMA)
Conyers, Rachel& Young, Sophie& Thomas, David M.. Liposarcoma : Molecular Genetics and Therapeutics. Sarcoma. 2010. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-475177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475177